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Mifepristone
The first of two medications used for a medication abortion (commonly known as the “abortion pill”). It has been legal in the US for nearly two decades, and has a safety record of over 99%. It blocks the hormone progesterone, stopping the pregnancy from continuing.
Misoprostol
The second of two medications used for a medication abortion. It is taken 24-48 hours after the Mifepristone. It is FDA-approved when used with Mifepristone to end an early pregnancy. It causes the uterus to empty, resulting in an experience similar to a heavy, crampy period or early miscarriage.
These medications have additional uses as well:
- Mifepristone is also used for cervical preparation for 2nd trimester abortion, and management of 2nd and 3rd trimester pregnancies when the fetus has died before birth.
- Misoprostol is also used for induction of labor, cervical ripening before surgical procedures, the treatment of postpartum hemorrhage, and to prevent stomach ulcers.